- Nagata R, Sato H, Takenaka S, Yokoyama J, Terai S, Mimuro H, Noiri Y.
Analysis of Genetic Relatedness between Gastric and Oral Helicobacter pylori in Patients with Early Gastric Cancer Using Multilocus Sequence Typing.
Int J Mol Sci 24(3) (2023) - 三室仁美、みにれびゅう「ピロリ菌の持続感染メカニズム」、Journal of Japanese Biochemical Society 95(1): 100-103 (2023)
- Hidehiko Kikuchi, Kaori Harata, Sumiko Akiyoshi, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi
Bifunctional activity of tangeretin (5,6,7,8,4'-pentamethoxyflavone) in suppression of cell growth and gene expression of the superoxide-generating system-related proteins in U937 cells
Fundamental Toxicological Sciences 9(5) 151-157 (2022) - Current Topics,, 小さなRNAが制御するピロリ菌の環境適応、持続感染と胃がん。木下遼, 三室仁美; 実験医学, Vol.39, No.14 (9月号), 2246-2249. (2021)
- Kinoshita-Daitoku R, Kiga K, Miyakoshi M, Otsubo R, Ogura Y, Sanada T, Bo Z, Phuoc TV, Okano T, Iida T, Yokomori R, Kuroda E, Hirukawa S, Tanaka M, Sood A, Subsomwong P, Ashida H, Binh TT, Nguyen LT, Van KV, Ho DQD, Nakai K, Suzuki T, Yamaoka Y, Hayashi T, Mimuro H.
A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment
Nat Commun. 12(1):2085. doi: 10.1038/s41467-021-22317-7. (2021) - Kubota-Aizawa S, Matsubara Y, Kanemoto H, Mimuro H, Uchida K, Chambers J, Tsuboi M, Ohno K, Fukushima K, Kato N, Yotsuyanagi H, Tsujimoto H.
Transmission of Helicobacter pylori between a human and two dogs: A case report
Helicobacter . 2021 Apr 5:e12798. doi: 10.1111/hel.12798. (2021) - Jinhyeob Ryu, Ryota Otsubo, Hiroshi Ashida, Tamako Iida, Akio Abe, Chihiro Sasakawa, Hitomi Mimuro
CBL-C E3 ubiquitin ligase acts as a host defense to mediate ubiquitin-proteasomal degradation of enteropathogenic Escherichia coli Tir protein
bioRxiv. doi: https://doi.org/10.1101/2021.03.08.434331 (2021) - Kinoshita-Daitoku R, Ogura Y, Kiga K, Maruyama F, Kondo T, Nakagawa I, Hayashi T, Mimuro H.
Complete Genome Sequence of Helicobacter pylori Strain ATCC 43504, a Type Strain That Can Infect Gerbils.
Microbiol Resour Announc. 9(18). pii: e00105-20. doi: 10.1128/MRA.00105-20. (2020) - Satoh-Takayama N, Kato T, Motomura Y, Kageyama T, Taguchi-Atarashi N, Kinoshita-Daitoku R, Kuroda E, Di Santo JP, Mimuro H, Moro K, Ohno H.
Bacteria-Induced Group 2 Innate Lymphoid Cells in the Stomach Provide Immune Protection through Induction of IgA.
Immunity. 52(4):635-649. (2020) - Ryo Kinoshita-Daitoku, Kotaro Kiga, Ryota Otsubo, Yoshitoshi Ogura, Takahito Sanada, Zhu Bo, Tuan Vo Phuoc, Tokuju Okano, Tamako Iida, Rui Yokomori, Eisuke Kuroda, Sayaka Hirukawa, Mototsugu Tanaka, Arpana Sood, Phawinee Subsomwong, Hiroshi Ashida, Tran Thanh Binh, Lam Tung Nguyen, Khien Vu Van, Dang Quy Dung Ho, Kenta Nakai, Toshihiko Suzuki, Yoshio Yamaoka, Tetsuya Hayashi, Hitomi Mimuro
Helicobacter small RNA regulates host adaptation and carcinogenesis
bioRxiv. doi: https://doi.org/10.1101/2020.02.15.950279 (2020) - Kinoshita-Daitoku R, Kiga K, Sanada T, Ogura Y, Bo Z, Iida T, Yokomori R, Kuroda E, Tanaka M, Sood A, Suzuki T, Nakai K, Hayashi T, Mimuro H.
Mutational diversity in mutY deficient Helicobacter pylori and its effect on adaptation to the gastric environment.
Biochem Biophys Res Commun. pii: S0006-291X(20)30361-2. doi: 10.1016/j.bbrc.2020.02.087. (2020) - Tanaka M*, Kinoshita-Daitoku R, Kiga K, Sanada T, Zhu B, Okano T, Aikawa C, Iida T, Ogura Y, Hayashi T, Okubo K, Kurosawa M, Hirahashi J, Suzuki T, Nakagawa I, Nangaku M, Mimuro H*.
Group A Streptococcus establishes pharynx infection by degrading the deoxyribonucleic acid of neutrophil extracellular traps.
Sci Rep. 10(1):3251 (2020) - Nakamura Y, Mimuro H, Kunisawa J, Furusawa Y, Takahashi D, Fujimura Y, Kaisho T, Kiyono H, Hase K.
Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity.
Mucosal Immunol. doi: 10.1038/s41385-020-0263-0. (2020) - Kikuchi H, Mimuro H, Madhyastha H, Kuribayashi F.
Chalcone skeleton promotes transcription of gp91-phox gene but inhibits expression of gp91-phox protein, and hydroxyl groups in hydroxychalcones participate in the stable expression of gp91-phox protein.
Microbiol Immunol. 63(10):438-443 (2019) - Morita N, Umemoto E, Fujita S, Hayashi A, Kikuta J, Kimura I, Haneda T, Imai T, Inoue A, Mimuro H, Maeda Y, Kayama H, Okumura R, Aoki J, Okada N, Kida T, Ishii M, Nabeshima R, Takeda K.
GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites.
Nature. 566(7742):110-114 (2019) - Nosaka K, Uchiyama R, Tadano K, Endo Y, Hayashi M, Konno H, Mimuro H.
Thiamin transport in Helicobacter pylori lacking the de novo synthesis of thiamin.
Microbiology. 165(2):224-232 (2019) - Otsubo R, Mimuro H*, Ashida H, Hamazaki J, Murata S, Sasakawa C*.
Shigella effector IpaH4.5 targets 19S regulatory particle subunit RPN13 in the 26S proteasome to dampen cytotoxic T lymphocyte activation.
Cell Microbiol. 21(3):e12974 (2019) - Tashima T, Nagatoishi S, Caaveiro JMM, Nakakido M, Sagara H, Kusano-Arai O, Iwanari H, Mimuro H, Hamakubo T, Ohnuma SI, Tsumoto K.
Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin.
Commun Biol. 1:33. doi: 10.1038/s42003-018-0038-2. eCollection (2018) - Wada Y, Takemura K, Tummala P, Uchida K, Kitagaki K, Furukawa A, Ishige Y, Ito T, Hara Y, Suzuki T, Mimuro H, Board PG, Eishi Y.
Helicobacter pylori induces somatic mutations in TP53 via overexpression of CHAC1 in infected gastric epithelial cells.
FEBS Open Bio. 8(4):671-679 (2018) - Ohishi T, Masuda T, Abe H, Hayashi C, Adachi H, Ohba SI, Igarashi M, Watanabe T, Mimuro H, Amalia E, Inaoka DK, Mochizuki K, Kita K, Shibasaki M, Kawada M.
Monotherapy with a novel intervenolin derivative, AS-1934, is an effective treatment for Helicobacter pylori infection.
Helicobacter. 23(2):e12470 (2018) - Hirukawa S, Sagara H, Kaneto S, Kondo T, Kiga K, Sanada T, Kiyono H, Mimuro H.
Characterization of morphological conversion of Helicobacter pylori under anaerobic conditions.
Microbiol Immunol. 62(4):221-228 (2018) - Shibata N, Kunisawa J, Hosomi K, Fujimoto Y, Mizote K, Kitayama N, Shimoyama A, Mimuro H, Sato S, Kishishita N, Ishii KJ, Fukase K, Kiyono H.
Lymphoid tissue-resident Alcaligenes LPS induces IgA production without excessive inflammatory responses via weak TLR4 agonist activity.
Mucosal Immunol. in press (2018) - Suzuki S, Suzuki T, Mimuro H, Mizushima T, & Sasakawa C.
Shigella hijacks the glomulin-cIAPs-inflammasome axis to promote inflammation.
EMBO Rep. 19(1):89-101 (2018) - Kikuchi H, Mimuro H, & Kuribayashi F.
Resveratrol strongly enhances the retinoic acid-induced superoxide generating activity via up-regulation of gp91-phox gene expression in U937 cells.
Biochem Biophys Res Commun. 495(1):1195-1200 (2018) - Kubota-Aizawa S, Ohno K, Fukushima K, Kanemoto H, Nakashima K, Uchida K, Chambers JK, Goto-Koshino Y, Watanabe T, Sekizaki T, Mimuro H, & Tsujimoto H.
Epidemiological study of gastric Helicobacter spp. in dogs with gastrointestinal disease in Japan and diversity of Helicobacter heilmannii sensu stricto.
Vet J. 225:56-62 (2017) - Kubota-Aizawa S, Ohno K, Kanemoto H, Nakashima K, Fukushima K, Uchida K, Chambers JK, Goto-Koshino Y, Mimuro H, Watanabe T, Sekizaki T, & Tsujimoto H.
Epidemiological study on feline gastric Helicobacter spp. in Japan.
J Vet Med Sci. 79(5):876-880 (2017) - Kikuchi, H., Nakayama, M., Kuribayashi, F., Mimuro, H., Imajoh-Ohmi, S., Nishitoh, H., & Nakayama, T.
Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells.
Biochem Biophys Res Commun. 467, 509-513 (2015) - Ogawa, H., Fujikura, D., Ohnuma, M., Ohnishi, N., Hang'ombe, B.M., Mimuro, H., Ezaki, T., Mweene, A.S., & Higashi, H.
A Novel Multiplex Pcr Discriminates Bacillus Anthracis and Its Genetically Related Strains from Other Bacillus Cereus Group Species.
PLoS One. 10, e0122004 (2015). - Kikuchi, H., Nakayama, M., Kuribayashi, F., Mimuro, H., Imajoh-Ohmi, S., Nishitoh, H., Takami, Y., & Nakayama, T.
Paired Box Gene 5 Isoforms a and B Have Different Functions in Transcriptional Regulation of B Cell Development-Related Genes in Immature B Cells.
Microbiol Immunol. 59, 426-431 (2015). - Kikuchi, H., Nakayama, M., Kawai, C., Kuribayashi, F., Mimuro, H., Imajoh-Ohmi, S., Nishitoh, H., Takami, Y., & Nakayama, T.
Histone Acetyltransferase P300/Cbp-Associated Factor Is an Effective Suppressor of Secretory Immunoglobulin Synthesis in Immature B Cells.
Microbiol Immunol. 59, 243-247 (2015). - Kikuchi, H., Kuribayashi, F., Mimuro, H., Imajoh-Ohmi, S., Nakayama, M., Takami, Y., Nishitoh, H., & Nakayama, T.
Lack of Gcn5 Remarkably Enhances the Resistance against Prolonged Endoplasmic Reticulum Stress-Induced Apoptosis through up-Regulation of Bcl-2 Gene Expression.
Biochem Biophys Res Commun. 463, 870-875 (2015). - Ashida, H., Mimuro, H., & Sasakawa, C.
Shigella Manipulates Host Immune Responses by Delivering Effector Proteins with Specific Roles.
Front Immunol. 6, 219 (2015). - Kiga, K.*, Mimuro, H.*, Suzuki, M., Shinozaki-Ushiku, A., Kobayashi, T., Sanada, T., Kim, M., Ogawa, M., Iwasaki, Y.W., Kayo, H., Fukuda-Yuzawa, Y., Yashiro, M., Fukayama, M., Fukao, T., & Sasakawa, C.
Epigenetic Silencing of Mir-210 Increases the Proliferation of Gastric Epithelium During Chronic Helicobacter Pylori Infection.
Nat Commun. 5, 4497 (2014). *Equally contributed first author - Suzuki, S., Mimuro, H., Kim, M., Ogawa, M., Ashida, H., Toyotome, T., Franchi, L., Suzuki, M., Sanada, T., Suzuki, T., Tsutsui, H., Nunez, G., & Sasakawa, C.
Shigella Ipah7.8 E3 Ubiquitin Ligase Targets Glomulin and Activates Inflammasomes to Demolish Macrophages.
Proc Natl Acad Sci U S A. 111, E4254-4263 (2014). - Muramoto, Y., Shoemaker, J.E., Le, M.Q., Itoh, Y., Tamura, D., Sakai-Tagawa, Y., Imai, H., Uraki, R., Takano, R., Kawakami, E., Ito, M., Okamoto, K., Ishigaki, H., Mimuro, H., Sasakawa, C., Matsuoka, Y., Noda, T., Fukuyama, S., Ogasawara, K., Kitano, H., & Kawaoka, Y.
Disease Severity Is Associated with Differential Gene Expression at the Early and Late Phases of Infection in Nonhuman Primates Infected with Different H5n1 Highly Pathogenic Avian Influenza Viruses.
J Virol. 88, 8981-8997 (2014). - Irving, A.T., Mimuro, H., Kufer, T.A., Lo, C., Wheeler, R., Turner, L.J., Thomas, B.J., Malosse, C., Gantier, M.P., Casillas, L.N., Votta, B.J., Bertin, J., Boneca, I.G., Philpott, D.J., Ferrero, R.L., & Kaparakis-Liaskos, M.
The Immune Receptor Nod1 and Kinase Rip2 Interact with Bacterial Peptidoglycan on Early Endosomes to Promote Autophagy and Inflammatory Signaling.
Cell Host Microbe. 15, 623-635 (2014). - 三室仁美.
Helicobacter pylori感染による宿主応答.
日本ヘリコバクター学会誌, 16, 32-38 (2014) - Suzuki, S., Franchi, L., He, Y., Munoz-Planillo, R., Mimuro, H., Suzuki, T., Sasakawa, C., & Nunez, G.
Shigella Type Iii Secretion Protein Mxii Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation Independently of Pkcdelta.
PLoS Pathog. 10, e1003926 (2014). - Kobayashi, T., Ogawa, M., Sanada, T., Mimuro, H., Kim, M., Ashida, H., Akakura, R., Yoshida, M., Kawalec, M., Reichhart, J.M., Mizushima, T., & Sasakawa, C.
The Shigella Ospc3 Effector Inhibits Caspase-4, Antagonizes Inflammatory Cell Death, and Promotes Epithelial Infection.
Cell Host Microbe. 13, 570-583 (2013). - Mimuro, H.
Helicobacter pylori 感染による宿主応答制御.
Journal of Helicobacter Research 17 (5) 423-429 (2013). - Mimuro, H.
Helicobacter pylori and Gastric Cancer: From a View Point of Microbiology.
Pathology and Clinical Medicine 31 (2) 173-179 (2013) - Sanada, T., Kim, M., Mimuro, H., Suzuki, M., Ogawa, M., Oyama, A., Ashida, H., Kobayashi, T., Koyama, T., Nagai, S., Shibata, Y., Gohda, J., Inoue, J., Mizushima, T., & Sasakawa, C.
The Shigella Flexneri Effector Ospi Deamidates Ubc13 to Dampen the Inflammatory Response.
Nature. 483, 623-626 (2012). - Fukumatsu, M., Ogawa, M., Arakawa, S., Suzuki, M., Nakayama, K., Shimizu, S., Kim, M., Mimuro, H., & Sasakawa, C.
Shigella Targets Epithelial Tricellular Junctions and Uses a Noncanonical Clathrin-Dependent Endocytic Pathway to Spread between Cells.
Cell Host Microbe. 11, 325-336 (2012). - Ashida, H., Ogawa, M., Kim, M., Mimuro, H., & Sasakawa, C.
Bacteria and Host Interactions in the Gut Epithelial Barrier.
Nat Chem Biol. 8, 36-45 (2012). - Sanada, T., Kim, M., Mimuro, H., Ashida, H., Ogawa, M., Mizushima, T., & Sasakawa, C.
A Bacterial Effector Targets the Traf6-Nfkappab Pathway to Modulate the Acute Inflammatory Response to Bacterial Invasion of Epithelial Cells.
Virulence. 3, 518-521 (2012). - Fukumatsu, M., Ogawa, M., Kim, M., Mimuro, H., & Sasakawa, C.
Uptake of Shigella-Containing Pseudopodia by Neighboring Epithelial Cells at Tricellular Junctions Via Non-Canonical Clathrin-Dependent Trafficking Pathway.
Virulence. 3, 515-518 (2012). - Suzuki, M., Kiga, K., Kersulyte, D., Cok, J., Hooper, C.C., Mimuro, H., Sanada, T., Suzuki, S., Oyama, M., Kozuka-Hata, H., Kamiya, S., Zou, Q.M., Gilman, R.H., Berg, D.E., & Sasakawa, C.
Attenuated Caga Oncoprotein in Helicobacter Pylori from Amerindians in Peruvian Amazon.
J Biol Chem. 286, 29964-29972 (2011). - Ogawa, M., Yoshikawa, Y., Kobayashi, T., Mimuro, H., Fukumatsu, M., Kiga, K., Piao, Z., Ashida, H., Yoshida, M., Kakuta, S., Koyama, T., Goto, Y., Nagatake, T., Nagai, S., Kiyono, H., Kawalec, M., Reichhart, J.M., & Sasakawa, C.
A Tecpr1-Dependent Selective Autophagy Pathway Targets Bacterial Pathogens.
Cell Host Microbe. 9, 376-389 (2011). - Ishijima, N., Suzuki, M., Ashida, H., Ichikawa, Y., Kanegae, Y., Saito, I., Boren, T., Haas, R., Sasakawa, C., & Mimuro, H.*
Baba-Mediated Adherence Is a Potentiator of the Helicobacter Pylori Type Iv Secretion System Activity.
J Biol Chem. 286, 25256-25264 (2011). - Ogawa, M., Yoshikawa, Y., Mimuro, H., Hain, T., Chakraborty, T., & Sasakawa, C.
Autophagy Targeting of Listeria Monocytogenes and the Bacterial Countermeasure.
Autophagy. 7, 310-314 (2011). - Ogawa, M., Mimuro, H., Yoshikawa, Y., Ashida, H., & Sasakawa, C.
Manipulation of Autophagy by Bacteria for Their Own Benefit.
Microbiol Immunol. 55, 459-471 (2011). - Ashida, H., Ogawa, M., Mimuro, H., Kobayashi, T., Sanada, T., & Sasakawa, C.
Shigella Are Versatile Mucosal Pathogens That Circumvent the Host Innate Immune System.
Curr Opin Immunol. 23, 448-455 (2011). - Ashida, H., Ogawa, M., Kim, M., Suzuki, S., Sanada, T., Punginelli, C., Mimuro, H., & Sasakawa, C.
Shigella Deploy Multiple Countermeasures against Host Innate Immune Responses.
Curr Opin Microbiol. 14, 16-23 (2011). - Ashida, H., Mimuro, H., Ogawa, M., Kobayashi, T., Sanada, T., Kim, M., & Sasakawa, C.
Cell Death and Infection: A Double-Edged Sword for Host and Pathogen Survival.
J Cell Biol. 195, 931-942 (2011). - Morikawa, H., Kim, M., Mimuro, H., Punginelli, C., Koyama, T., Nagai, S., Miyawaki, A., Iwai, K., & Sasakawa, C.
The Bacterial Effector Cif Interferes with Scf Ubiquitin Ligase Function by Inhibiting Deneddylation of Cullin1.
Biochem Biophys Res Commun. 401, 268-274 (2010). - Kim, M., Ashida, H., Ogawa, M., Yoshikawa, Y., Mimuro, H., & Sasakawa, C.
Bacterial Interactions with the Host Epithelium.
Cell Host Microbe. 8, 20-35 (2010). - Backert, S., Mimuro, H., Israel, D. A., and Peek, J., R.M.
Virulence factors of Helicobacter pylori, In Helicobacter pylori in the 21st Century, P. Sutton, and H. Mitchell, eds. (Wallingford, UK: CAB International), 212-247 (2010). - 三室 仁美, 笹川 千尋.
病原微生物と粘膜免疫ー細菌による粘膜感染, 臨床粘膜免疫学, 清野 宏 編 (シナジー), pp. 466-477 (2010) - Kim, M., Ogawa, M., Mimuro, H., & Sasakawa, C.
Reinforcement of Epithelial Cell Adhesion to Basement Membrane by a Bacterial Pathogen as a New Infectious Stratagem.
Virulence. 1, 52-55 (2010). - Yoshikawa, Y., Ogawa, M., Hain, T., Yoshida, M., Fukumatsu, M., Kim, M., Mimuro, H., Nakagawa, I., Yanagawa, T., Ishii, T., Kakizuka, A., Sztul, E., Chakraborty, T., & Sasakawa, C.
Listeria Monocytogenes Acta-Mediated Escape from Autophagic Recognition.
Nat Cell Biol. 11, 1233-1240 (2009). - Suzuki, M., Mimuro, H., Kiga, K., Fukumatsu, M., Ishijima, N., Morikawa, H., Nagai, S., Koyasu, S., Gilman, R.H., Kersulyte, D., Berg, D.E., & Sasakawa, C.
Helicobacter Pylori Caga Phosphorylation-Independent Function in Epithelial Proliferation and Inflammation.
Cell Host Microbe. 5, 23-34 (2009). - Nochi, T., Yuki, Y., Katakai, Y., Shibata, H., Tokuhara, D., Mejima, M., Kurokawa, S., Takahashi, Y., Nakanishi, U., Ono, F., Mimuro, H., Sasakawa, C., Takaiwa, F., Terao, K., & Kiyono, H.
A Rice-Based Oral Cholera Vaccine Induces Macaque-Specific Systemic Neutralizing Antibodies but Does Not Influence Pre-Existing Intestinal Immunity.
J Immunol. 183, 6538-6544 (2009). - Nagatake, T., Fukuyama, S., Kim, D.Y., Goda, K., Igarashi, O., Sato, S., Nochi, T., Sagara, H., Yokota, Y., Jetten, A.M., Kaisho, T., Akira, S., Mimuro, H., Sasakawa, C., Fukui, Y., Fujihashi, K., Akiyama, T., Inoue, J., Penninger, J.M., Kunisawa, J., & Kiyono, H.
Id2-, Rorgammat-, and Ltbetar-Independent Initiation of Lymphoid Organogenesis in Ocular Immunity.
J Exp Med. 206, 2351-2364 (2009). - Nagamatsu, K., Kuwae, A., Konaka, T., Nagai, S., Yoshida, S., Eguchi, M., Watanabe, M., Mimuro, H., Koyasu, S., & Abe, A.
Bordetella Evades the Host Immune System by Inducing Il-10 through a Type Iii Effector, Bopn.
J Exp Med. 206, 3073-3088 (2009). - Bronte-Tinkew, D.M., Terebiznik, M., Franco, A., Ang, M., Ahn, D., Mimuro, H., Sasakawa, C., Ropeleski, M.J., Peek, R.M., Jr., & Jones, N.L.
Helicobacter Pylori Cytotoxin-Associated Gene a Activates the Signal Transducer and Activator of Transcription 3 Pathway in Vitro and in Vivo.
Cancer Res. 69, 632-639 (2009). - Ashida, H., Ogawa, M., Mimuro, H., & Sasakawa, C.
Shigella Infection of Intestinal Epithelium and Circumvention of the Host Innate Defense System.
Curr Top Microbiol Immunol. 337, 231-255 (2009). - Mimuro, H.
Strategy of Helicobacter pylori to enhance colonization of the stomach.
Nippon Saikingaku Zasshi 64, 311-317, 2009 - Mimuro, H.
ヘリコバクターピロリの胃上皮感染機構 Control of gastric epithelium by Helicobacter pylori infection.
実験医学増刊 27, 1590-1597 (2009) - Mimuro, H.*, Berg, D.E., & Sasakawa, C.
Control of Epithelial Cell Structure and Developmental Fate: Lessons from Helicobacter Pylori.
Bioessays. 30, 515-520 (2008). - Mimuro, H.
Helicobacter pylori病原性新たなる発見ーHelicobacter pyloriの胃上皮感染戦略と病原因子CagAの生物活性.
Helicobacter Research 12, 37-43 (2008) - Suzuki, T., Franchi, L., Toma, C., Ashida, H., Ogawa, M., Yoshikawa, Y., Mimuro, H., Inohara, N., Sasakawa, C., & Nunez, G.
Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy Via Ipaf and Asc in Shigella-Infected Macrophages.
PLoS Pathog. 3, e111 (2007). - Nagai, S., Mimuro, H., Yamada, T., Baba, Y., Moro, K., Nochi, T., Kiyono, H., Suzuki, T., Sasakawa, C., & Koyasu, S.
Role of Peyer's Patches in the Induction of Helicobacter Pylori-Induced Gastritis.
Proc Natl Acad Sci U S A. 104, 8971-8976 (2007). - Mimuro, H., Suzuki, T., Nagai, S., Rieder, G., Suzuki, M., Nagai, T., Fujita, Y., Nagamatsu, K., Ishijima, N., Koyasu, S., Haas, R., & Sasakawa, C.
Helicobacter Pylori Dampens Gut Epithelial Self-Renewal by Inhibiting Apoptosis, a Bacterial Strategy to Enhance Colonization of the Stomach.
Cell Host Microbe. 2, 250-263 (2007). - Suzuki, M., Mimuro, H., Suzuki, T., Park, M., Yamamoto, T., & Sasakawa, C.
Interaction of Caga with Crk Plays an Important Role in Helicobacter Pylori-Induced Loss of Gastric Epithelial Cell Adhesion.
J Exp Med. 202, 1235-1247 (2005). - Tomita, T., Noguchi, K., Mimuro, H., Ukaji, F., Ito, K., Sugawara-Tomita, N., & Hashimoto, Y.
Pleurotolysin, a Novel Sphingomyelin-Specific Two-Component Cytolysin from the Edible Mushroom Pleurotus Ostreatus, Assembles into a Transmembrane Pore Complex.
J Biol Chem. 279, 26975-26982 (2004). - Tanaka, J., Suzuki, T., Mimuro, H., & Sasakawa, C.
Structural Definition on the Surface of Helicobacter Pylori Type Iv Secretion Apparatus.
Cell Microbiol. 5, 395-404 (2003). - Nonaka, T., Kuwabara, T., Mimuro, H., Kuwae, A., & Imajoh-Ohmi, S.
Shigella-Induced Necrosis and Apoptosis of U937 Cells and J774 Macrophages.
Microbiology. 149, 2513-2527 (2003). - Yoshida, S., Katayama, E., Kuwae, A., Mimuro, H., Suzuki, T., & Sasakawa, C.
Shigella Deliver an Effector Protein to Trigger Host Microtubule Destabilization, Which Promotes Rac1 Activity and Efficient Bacterial Internalization.
EMBO J. 21, 2923-2935 (2002). - Suzuki, T., Mimuro, H., Suetsugu, S., Miki, H., Takenawa, T., & Sasakawa, C.
Neural Wiskott-Aldrich Syndrome Protein (N-Wasp) Is the Specific Ligand for Shigella Virg among the Wasp Family and Determines the Host Cell Type Allowing Actin-Based Spreading.
Cell Microbiol. 4, 223-233 (2002). - Mimuro, H., Suzuki, T., Tanaka, J., Asahi, M., Haas, R., & Sasakawa, C.
Grb2 Is a Key Mediator of Helicobacter Pylori Caga Protein Activities.
Mol Cell. 10, 745-755 (2002). - Kuwae, A., Yoshida, S., Tamano, K., Mimuro, H., Suzuki, T., & Sasakawa, C.
Shigella Invasion of Macrophage Requires the Insertion of Ipac into the Host Plasma Membrane. Functional Analysis of Ipac.
J Biol Chem. 276, 32230-32239 (2001). - Suzuki, T., Mimuro, H., Miki, H., Takenawa, T., Sasaki, T., Nakanishi, H., Takai, Y., & Sasakawa, C.
Rho Family Gtpase Cdc42 Is Essential for the Actin-Based Motility of Shigella in Mammalian Cells.
J Exp Med. 191, 1905-1920 (2000). - Mimuro, H., Suzuki, T., Suetsugu, S., Miki, H., Takenawa, T., & Sasakawa, C.
Profilin Is Required for Sustaining Efficient Intra- and Intercellular Spreading of Shigella Flexneri.
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